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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5371867f9a2992774602c748b800b66321e9ab4ca5dd19eb95898f0fc82b72c' 
  AND token = 'Y+Kewtg0aUTWPDJXdTL6Joavfe73gvJ/p8/c/4D11WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}