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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f2c4e813248d2005910b1dce9e21a91e17f7c0e37e7b770f045b60ec5c313d' 
  AND token = 'zgAHjWnIuT+8U29LL1MoAcSgASK3uw3l7bF17bC0xFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}