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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541a7b8c9392742e516fc04f7cf2289d1b16a744889a35a8862b55f57a7d556b' 
  AND token = '9Clq13jrEF4R2YYDn8Msj/KbSqNi3O4mfpZLWnBXod0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}