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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0072e8ad19bdac263322d0f4f1434e2729b788d3ca4b12bb894416447c6450cd' 
  AND token = 'MzyZZN1B30tfnYlRlzxKC5qV6p+d6ewyifsDVgPll7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}