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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9318aa2efe0d1239065887ebb39f106022f00f3f0435d31ab1ec64a2ee1b39b0' 
  AND token = 'cHg06CAtL6WF3N7U5EYuiE2qK4/UsxZ77Kt9pTbsmzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}