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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5c9e8a59ec91843f8284c4e69d8cf2ae868473a40aa69531af0c3ba29d9647' 
  AND token = 'psdCK2cg31Bh2SRYqSclPpLhwRm/59LOW7ieONPNhgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}