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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0cb14b9cef542397f18f9fbe9f4a19a453106aa0e59c081c456106614fd842c' 
  AND token = '8vazNfwusD6H+onSq6lXSSTBL3M++TGurFeKzAg5OWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}