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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ac346a650d36968b7f0bc0d83fd1a2b99118043b468822e7eeb6723b8873cb' 
  AND token = 'tz+VS7oGiciHhvCtIvhFhqr3fFaR8/ettMW26eRkxRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}