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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60a5936ff8e344db486327417a1e07953c3d1bee05564dcf0967a59f29e6fa20' 
  AND token = 'vQYHFTJDUoa5kQX3fUyTHFmNFVR1gRJzmOr8AK+Y9QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}