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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a563c3624480ce80df140159f94b0e601219aadd8bdac098d05e1427eae59b6b' 
  AND token = 'CB0YxmBECHOTfAaCYvhqS3SNXK3heVhGQpAn6n8KpxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}