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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d441e0321eef51992fc2603df70b88bcd073fe37048ee6765aca961f687f5e' 
  AND token = 'C+poKQxv9un3woIeyKMQ0gi3++MIZ+OP7UH+pA2uNYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}