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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f85bd78662f27663d8918d8b2d43d15c50e6a58a6801a74775147f6f7ca231' 
  AND token = 'YTMP7Y0GokoRonj3H63bujSfySxquGdHqvSBAmfSQdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}