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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c4b1f4121b2f0484bfc917096b5eed25bb153b083957e0287b0777b38f9b04' 
  AND token = '4ikwvwFfixTxyjSZqpQTVdNHRTyoAUVyBtXm0uF55Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}