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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7f25a56d1b75e9e76ba21d74dd16643ac6d74f3cc4145ba3e67a124421680b' 
  AND token = 'mbSFAMpj2pt3+SP1rGigRZfIFWoV+Mvo7R3NjhVRBq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}