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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859d04e29b3d6b1e7f4cf599b16410ed7b3b71e5d0c2ddb557315bc761cf5887' 
  AND token = '2fU+XyNaTxcR7VRwMBdiLAd8r7IJbMt6dBtZn8AgKhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}