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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23517b565743bc323ccda2f89750ac6e5431ba485f2641244f36e0730e373b37' 
  AND token = 'O+SLp57IVuXNiNkIDzRbtMqfidna1kD9iTxbJN6bZyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}