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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b327d4ffa72a352a08944e7d2ba276afc1102f20a46ee9acce55ca78021a5c03' 
  AND token = 'sMTfOR+stCR/o0+dV5tC8oJ4GssipFLaGiU1j50u230=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}