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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c050b45b385b62a0bcdbe4c0836df0d604e593a8fa397f3a36ba0761caaf17' 
  AND token = 'f23/zkoTpRGh9bhG5Y2Vl+Keu9fI0h3OubW5bfiHNA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}