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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a8046f50abe8d618b0f006b655a05895ee36e21aa60fec3cba17921dde29c6' 
  AND token = 'P3IXwE7VVirDqtMTSoNX5XJ3xJGXOo3gdd/tctwKYqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}