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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f74e4c8af3388a354ed6212df81ef556808329897cc7b66e353f060831f76c' 
  AND token = 'AJ0Jrq/Q7A9xkLSozr443Letqxr5QpCjQ0nYDAV+kKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}