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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2d01aa42e6a24601da1015606cad7dccea3e72812876239b1a76b0d204b3e4' 
  AND token = '78wjSSzaFnr/0ClX5ykBF/r7R8WJ3S5aydKJh8Q4Y1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}