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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777ff7ea1c0f5d04ad1677815f2680ddfa99683a6f0e9a1cf2032c297694edc2' 
  AND token = 'uupH6wj9ne0bg92dLONxmNAUe1QRPr+d9TR7CdQJ3DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}