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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8c14abe63612a5760b1a5934293614ab5976b0ae33ea8b165e7bbe7794d6be' 
  AND token = 'Os31uNzGYAp3VPtFlissWmEXaZHIWTR9PXwtPd3ar0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}