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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558d3e5b001c185172824c9e4022c611abf3876802e65012b5315e6c1e1262f0' 
  AND token = 'a/mz9n2c+WgXfizt90HFlsh7pMxTgDa62OBhp19dFKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}