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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d8ea9f3f5e4f0f6c81000da1f07c6a6b6e7178b80ddf7a99b5489cf69cab79' 
  AND token = 'KDFhjexPUr1aOCk2tV/fy3Q5A0mwMz7hysMlBruESxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}