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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe48eba212413f7192543e3d0acb6d7d1f7678d63dc4bf445fd49dced35bf3e5' 
  AND token = '0Jh7r4kjNdZZHDxAycmqlUD93GNAncU6ctJw5C3KIbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}