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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2695d489433ee1eab89ee9d29962309edd5094acb48f52e7a5e244b562d6592' 
  AND token = 'NdGo2UltBKL0g+RZWzlWzYiCxa5VC0p84EG5MoN27CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}