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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e85b05f2fc13e71c06bea209f06f632ffd5ba68de69b17913f3e75e10b1ac52' 
  AND token = 'f3PUkdRgc3ZYG7NPoy3wMhXoY8nWLUiuA5GqU5oMgh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}