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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1646d0c3637fa82e6d85f85b1552dfb5ed03dc3decda9db967e4d577305834' 
  AND token = 'LyhhghDAfxhzkKmYSV33Q+zua68NhxGn2Ljmz4ggiyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}