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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8599a3e6ea1dd3eb4bd0824668de16b3ae84f4ffd1baafc05f026359a9aee408' 
  AND token = 'KciPK0gNv+tIU+JJ14j4sCm2y4zdfjtivsodtRuvPXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}