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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd528d28df83316e232c9abb716ab50f242e69f9e43acc4bfef20046114c479' 
  AND token = '2s0jyxrJ/73GGmSrT3Df58R5gMqC8o1vtdWzaXorJ8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}