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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca34781b3d4a845461b57fed4d6a5591b3aca7e3622238810bc480b05f87165d' 
  AND token = 'RMj9Z/CA7oUydhPNTKR6wiOzroxwGOAsPI1nAYPtstY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}