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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5582268fc086a0cd159c33b8ed5a8aac0db3d5c2dde117b3625f7a6f08aa7508' 
  AND token = 'PYNHw+rreWsSzcX987jOnrqdF5z/mHanZP1JvMTFwSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}