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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d72697d141f0f8f4fbdd5b1fb9782e7f64b0c1978a048e0606245b1c7521c1' 
  AND token = 'U/db5qKJXFhXllnnqtx0fTiUsygrFqD23iKXLyP5aHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}