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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd787ec238d0beba64c44fbdece92c97800122380ff8392003032357f0f126276' 
  AND token = 'Wpxe3aqDjrqtjWrnV3OqTZvtLFczK0JYbb9V4PWTiQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}