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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a8a227c88a2bf2035f8b1e454c7deca3c29a30c7a081f28f289fb06de04c07' 
  AND token = 'Ct2ha/Udf2AmcbSoXLTaF52S38QgjkorQfUQ3p8sW7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}