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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca307861c6b8eb74f28d7f2cb1dcb4396fe7d3028356284a78b2e75e0ac749d4' 
  AND token = 'RpcOgMAPZilE4ZU85vWM3P3fdnqrgYa+VRzBdxtnLq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}