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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f4edaab62beb7a2076ec5dc6aaf19c6e51cfc23036c2ea1fb2aafedcfdd43a5' 
  AND token = 'WP20KLEE/AG7n5gKe8vtWkNKmTfVyNuGHgB3pGPQfp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}