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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a25e739a86ce0f1fc0244dde90695a48dbe2e6cdcdd7e836e0cfe7d16214cb2' 
  AND token = 'pD6HPlf/E6YVMaPBCQBmTT0vGzWNwrsY+SybZl/pta0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}