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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e068f30ff2a9c220e72e17d9182d227be82bbda1181c35935c6d78d317b1c06' 
  AND token = 'hb6fqG95pnKj/dsGVeiS+1ws+IuIh1sbYqYPy6Lqs1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}