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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14233a7b307f5d329a0af23d0f857a5090f0cbd1649e0e0105773f365e118266' 
  AND token = 'oVK+Gf9b/UqbAOkYrvTnDX0ekpDzoEw3Yh9/kSUI/Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}