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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21ecb5ecccea8ccb5c4600dff011aeb745a361ec83c188585e91f50ff5411cd' 
  AND token = '/aKt0EI7lc3nYU3ITs/UHwZ/ibWlR17xLbw6fwnfMqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}