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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5969d44e0998c51d0937fd2b238bb43ba2ca3b10a67e08c8d84e904cd72756bf' 
  AND token = 'zc7qmEMWup2318woBCfBzTm8u2rDAubN7qmz3ilLc/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}