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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80946fb5547b55cdae16401fea3cb0366087286d1434bb921da15cb8706b0136' 
  AND token = 'USxbAgjp96YbM8ptrKmXV2Mi/0G34tnndb8ZcZ5uzJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}