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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e405aede4d255893d1eebfa47520fc2947f85d762c93a11606767f189bd455' 
  AND token = '+mpW3nbQ7Yx6Hmajj1x5SFRJe2XJ/eynK+EGpAdwQms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}