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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0cac80826c8624d606c610b17e2e524eb53c743596fa7d96623c555c9226ac0' 
  AND token = 'zvbY91ZzmjrjP0qvwmLjoa6rH7fjUKn6aRj8EL28I8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}