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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0275e6849d07f8fe1126f533f3d28e9fe639643ebf02b34d496acd502e36bf26' 
  AND token = 'AK95ionRqf9JmWWTlwkuh83I4JMKb+N6/duH8h0ZecQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}