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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0ca6a419d0ceb4f3d6aede6e5eb2f0c64d575d42cb619d1d09a77a0a2495af' 
  AND token = 'S6QZPsfUyf1xggafjClpfnheNQAQFMoNmOFqV+AnAI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}