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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28ad98b98b559e8594e6c8e14a5a53addca641acc32813121113d251f2750a73' 
  AND token = 'Ar9XmPe2+mpC8RGm0QPbVHOAOEftimRzWSgZ4JvPe74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}