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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ad187a20dab095b880a72fb222807cc0f835a212a23da4034b2969fb1d47d9' 
  AND token = 'Lj5Omkkisz+jQDZHe36tBzHwDfUsFjBQ+YE5bMhEXN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}